Biomolecules 12 (6), 815
Protocol design and informed consent dose, frequency, route, expected timeline, monitoring plan, and a clear acknowledgment that BPC-157 is not an FDA-approved finished drug
None of these failure modes are problems with the molecule itself
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Although TRP14 can reduce cystine in vitro (Pader et al, 2014) it is unknown whether TRP14 has this role in vivo, and it should be noted that although several Trx-fold proteins can catalyze reduction of cystine when directly assayed, this does not necessarily suggest they have that role in a physiological cell context